"My two dads" would have a completely different meaning today

...and Full House probably would too.

No, it would be about a man and a woman who are raising their teenage daughter, the woman transitions into a man and then spends the series trying to encourage their daughter to get on hormone therapy to become a man.

There would be a "very special episode" where ANTIFA would try and recruit the daughter to go burn down an Office Depot and protest the shooting of an armed black man who shot at cops and ended up being killed on video but only after the video was released cutting out the footage where the black man shot first. Al Sharpton would guest star and Kamala Harris and Lebron James would make a moving speech about how blacks are oppressed and can't get anywhere in life because the white man is getting them down. After the speech they get into Lebron's pimped out Escalade and drive away.

it would be called 2 and a half men but the daughter’s a son

Rename “My Two Likely Not Gay Dads”

Before "gay marriage" millions of gay fathers and gay couples have raised their children from previous heterosexual relationships. I knew many such folks in the 80's and 90's. We didn't just land from Mars, ya know.

So what. Sounds like a funny premise for a show.