Let's talk BUSINESS: movie is performing worse than Black Widow. It seems it's gonna be a BIG flop.

OW has been $71M domestic. In comparison, Black Window had a $80M OW. F9 had a $70M OW. That suggests Shang-Chi will be in the top part of the year, domestic, in a close tie with the other ones.
https://www.boxofficemojo.com/release/rl2122089985/weekend

Let's not forget that Black Widow was simultaneously released in internet. This one wasn't, and it still performed lower than Black Widow.

Besides that, in 2021 Disney movies are not doing that well worldwide. Disney has only placed 2 movies in the top 10 worldwide this year, with Black Widow, top Disney movie until now, being only #5 worldwide.
https://www.boxofficemojo.com/year/world

It's hard to know the real budget. In the last years Disney only releases info about the budget after they have info about the box office, which suggests they "adjust" it. Info was released yesterday about Shang-Chi having a $150M budget, which is a low one for a MCU movie. That's hard to believe, though. This is the first movie in the new cycle, the one that's supposed to get people engaged. Why would they cut costs precisely here?. The most logical explanation is that they think the movie is underperforming, so they're releasing a lower budget.

If the real budget was $200M, a normal MCU one, which is a more credible number, break even would be about $600 to $800M (approximately). Shang-Chi seems it's gonna perform worse than Black Widow and will end up being around $350M worldwide. That's a big flop.

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EDIT

After 4 weeks, it made $366M. It seems that final box office will be around $380M, more or less, same amount as Black Widow.

It's far from reaching break even, which means it was a flop. As usual, I was right.