Anyone ever see this?

Yes, and perhaps not

Couple were married in real life but now have long-since divorced.

Yes, I saw a marathon of this. It only ran for one season. It was a sitcom about a Jewish man married to a Catholic woman.

Apparently the real life couple first met while making this series.

Yes, I remember it and having a big crush on Merideth.

I remember watching this show as a kid. Didn't know they were married in real life. I seem to recall it was pretty entertaining.

One of my favorite shows as a kid. I thought it was great that the actors fell in love and married in real life. Their divorce was very sad news.