THIS WILL BE A FLOP
How can I tell? By the garish movie posters alone.
I predict that this movie, like Suicide Squad before it, will be one of THE worst movies this year.
The Harley Quin comic book has been in the top 3 best sellers for years and even occasionally pushed out #1 (Batman). I read a few issues and it sucks. So the fan base loves the character no matter what. They could make this movie worse than SS (and it kinda looks like it) and it will still get accolades.
It will be somewhat successful and get a sequel. If you hate it, you will transform into a racist/bigot/homophobe/misogynist immediately. There's money to be made in the pre-marginalized opinions game.