I wonder if we'll get flash-forwards of grown Sheldon, maybe with Amy or Leonard. And maybe as a way to further explain what will happen to the other characters too that we never hear of or see in the original show, like Sturgis, Paige
shareSturgis is rather old and could have died before TBBT started.
And Paige's future seems quite uncertain. With her intellect she could have a successful career. But she seems to be getting more and more self desctuctive in each episode. She still has plenlty of chances to get her act together, but her general trend so far is downward.