In the end, it is sad.

Why is the music very sad in the end, when Hawkins shed his tears?

Is it because it makes us realize we are all human? Physical attraction and contact are necessary in our relationships.

Even how humble he could have been because of his illness, the great scientist still could not stand to constantly act like not knowing his once-loving, sacrifying, patient, long-suffering wife is not in love with him any more.