Problems with the documentary, definitely.
There was very little if any discussion about what effect the drug was supposed to have on the limited number of test subjects -- arrest progression or reverse it?
There was zero discussion about Leslie's role on the research team -- as a mother of one of the patients she has a distinct conflict of interest in the results, so was she the leader, as the doc pretty much portrayed, or an just the founder? She does get Sam's results later in the film like any other participant, but that does not really obviate the conflict.
There was no mention of the two publications that rejected the paper, nor of the one that accepted it.
There was much filler involving mother Leslie's dedication and research -- it's like, okay, we get it -- wonderful woman and all -- but cutting it to size would have made the doc closer to an hour, which I think it should've been to begin with. Or, they could've added more interviews with the other kids in the study or even more with Sam himself; if you think about it, there's surprisingly little of it in the film.
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