Zoumas in series 2?
I'd love to see Zoumas in the sophomore year of Jessica Jones. Something about his casual, pragmatic demeanor really drew me into ALIAS, and helped set apart that this really was a "hero book" hemming closer to reality than ever, and NOT a superhero book with capes traded for trenchcoats. Bendis's wonderful writing had already made that fairly clear, but the appearance (and indifference) of Zoumas was what turned me into a ravenous fan.
Anyone else? I'd love a return to the "who's pulling my strings" paranoia of the first series without Kilgrave stealing the mystery away. Zoumas would do that nicely with his layer cake of puppetmastery.
As for whom... I would just adore to see Patrick Wilson play the sod. Wilson is a talented character actor that could easily achieve Zoumas's smarmy, phony niceties with veiled sinister threat at the core.