I think we have to assume there's a little more to it than just panic attacks and conventional agoraphobia. For one thing, no one is afraid of or injured by big open spaces, only by being outside in open air. The shopping mall and some of the underground spaces were huge, but there was no ill effect.
The syndrome, whatever it is, is activated specifically by being outside, presumably even in a small outside space (like a courtyard), although we don't actually see that. It causes more than just panic. It causes real physical damage that will lead to death very quickly (although not instantly, as some reviewers state). Exactly what damage the syndrome causes is not fully explained, but it's more than just fear and panic.
The story would have been more believable if victims had simply dropped dead with sudden cardiac death. Then, you could say that the syndrome provoked a fatal arrhythmia. That sort of makes sense, even if it is unlikely. Dressing up the deaths with seizures, bleeding from various orifices, disorientation, staggering around, etc., means that the cause of death was non-cardiac and therefore less believable.
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