They could have changed Mindy into making her less unlikeable...
Had it been something where he penetrated into her due to an accident, I could see her being somewhat likeable. Instead she was a dumb, "I'm so bohemian and different", type. None of the main characters were likeable.
Mindy- liar, stupid, pretentious
Fred- major liar, coward
Nelly- control freak (but of the 3, her being a control freak doesn't seem like that much of a fault).