Go to Hell
I really don't know what it is with this show. A friend mentioned it to me offhandedly to me one day, and it seemed something that would be right up my ally (had just finished watching Ugly Americans, which I loved), so I marked it off on my DVR. When I watched that first episode, I hated it. Didn't find it funny at all. But my girlfriend wanted to watch it too, so I ended up sitting through it again. The second time through I actually found it hysterical. The more I watched NEIGHBORS FROM HELL, the more I liked it. Watched the entire first season through maybe three times before finally erasing it.
Sure, it isn't up there with a lot of the other animated comedies, but damned if I didn't end up enjoying it.