when tosh interviews guests via skipe
The guest is pre recorded being interviewed by someone else, probably a producer, then for the show they playback the guest's footage and tosh pretends to be doing the interviews. JUST SO WE'RE CLEAR! whenever he gets big laughs for saying outlandish things to them, they're not even there live.
I don't always post on IMDB.com, but when I do I make sure I'm hammered.