We have no idea how reproduction works on Gallifrey, and I hope it's never explained in detail. The Doctor had a granddaughter and mentioned being a father once, in a distant and regretful way, that's about all we've got.
We have no idea how long-term relationships work either, but I suspect they don't have marriages. I mean humans have trouble keeping marriages going for even a few decades, even with sex and breeding to give them something in common, how could a species that has life spans somewhere between centuries-long and immortal maintain a pair bond when they have the potential to turn into different people with different personalities and different ages and occasionally even a different sex? I suppose that some people could love each other enough to stay together whether their partner is an old man or a little girl at the moment, but I would imagine that's unusual. Still, Missy seems to feel that way, the Doctor... less so.
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