Imagine how awkward it would be to be an actor in this...

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Actors? Excuse me. This movie had actors in it? I thought there are bunch of random friends of the director who participated in that...... movie...;

man those killers have no mercy nor show remorse towards their victims. Have they no conscious of their wicked most evil crimes. I would to place them in a room and give them a taste of their own medication but even worse. see how they then would like being laughed and screamed to death.

I'll bet they had a blast making this!!

I don't love her.. She kicked me in the face!!

Most of the, um, "actors" in these movies are just drinking buddies and/or relatives of the director and pretty much all sicko horror fans too (as far as I know), so I would think that helps the atmosphere remain fun on set compared to, say, if they were strangers meeting each other for the first time.

Also sort of related - on YouTube there's a "behind the scenes" clip from the filming of Human Centipede 2, where it shows the cast laughing, cracking jokes, singing stupid songs, etc. between takes of the most disgusting, gory scenes. So I think anyone who goes into a project like this knows how to separate fiction from reality.