How much is Masrani to blame?
While it was irresponsible for him to order Wu to make something that would look "cool" and "scary" without analyzing what animals they were using to engineer her, it's pretty clear that he didn't tell Wu "Oh by the way, make sure you design it to be completely and utterly sociopathic so that it goes out of its way to kill anything and everything it comes into contact with." But that's what Wu ended up doing because he was secretly in league with Hoskins the whole time, so those are the two men I assign most of the blame to. Plus unlike Wu and Hoskins, Masrani actually tried to correct the problem.
Modern left-wingers in a nutshell: https://m.youtube.com/watch?v=_tEiguYmgxA