The Real Reason The Show Was Canceled
Any Day Now ended after its initial four-season (88 episodes) contract expired. The show would have been renewed, but Annie Potts chose instead to care for her family. The series ended with Rene's marriage, as well as M.E. and Rene's mothers finally putting an end to their decades-long animosity.
it eneded because annie potts did not want to renew her contract.