Cast a shot-for-shot remake
The Colin Farrell movie was an 7-couric turd, but maybe Gus Van Sant could be persuaded to do a Psycho-style shot for shot remake?
Doug - Tom Hardy
Melina - Nathalie Emmanuel
Lori - Charlize Theron (a fun mirror image of their roles in Mad Max)
Cohaagen - Jeremy Irons (too easy)
Richter - Tom Hiddleston (I get chills thinking of him saying "not a chance" in Doug's apartment at the beginning)
George/Kuato - Ed Harris
Benny - John C. Reilly
Helm - Paul Bettany ("no, I'm sure she hated every minute of it!" His delivery of this would be perfect)
Dr. Edgemar - Stanley Tucci
and the one role I am 100% certain about...the part he was born to play...
Bob McClane - Bob Odenkirk