Lay Barnie Lay
In one episode, Barney causes a lot of commotion in town by re-opening a 19-year-old case in which Floyd The Barber and the local grocer where arrested for assault. Floyd The Barber remarks to Andy "I think the problem with Barney is that he's not married. If he was married, little things like this wouldn't bother him".
I think it's safe to say that Andy, Floyd and Barney are from a generation that did not believe in premarital sex. Therefore I suspect that when Floyd says little things wouldn't bother Barney if he was married, that's an old-timer's way of saying "that dude needs to get laid"