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"In addition to that, you may not have realized that the reason Dustin has the medical condition Cleidocranial dysplasia in the series, is because Gaten Matarazzo has the condition in real life. Cleidocranial dysplasia can cause abnormal development in the bones in the skull and clavicle area and explains why Dustin has no front teeth..." Found it on the Google, but there's a spoiler after it so I left that bit out.

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