I think he could be a great dramatic actor

He could also be a good villain. Sometimes he sounds assertive and some of his characters get angry.

He's good in 50/50.

I finished rereading "MASH" by Richard Hooker that the movie and TV series is based on.
For some reason I pictured Rogen as Trapper John McIntyre.

He can also try not to be the fat jewish guy everyone needs to be sorry for but don't see that one coming