Where could Gene Wilder's career have gone had his wife Gilda Radner not died in 1989?

It seemed like the combination of her death from cancer as well as he failure of his projects such as The Woman in Red, Haunted Honeymoon, and Another You removed his desire to work. Do you think that had he played his cards right, he could have moved into character roles a la Alan Arkin?

https://www.quora.com/Was-Gene-Wilder-one-of-the-big-American-comedy-actors-in-the-1980s-or-was-his-career-pretty-much-over-then