Sherilyn Fenn, Audrey Horne Twin Peaks spin-off, and Mulholland Drive
Seems that Mulholland Drive started out originally to be the Audrey Horne-Twin Peaks spin off series, and that Sherilyn Fenn inspired Lynch for the character of Rita in Mulholland Drive.
In a 1997 interview Fenn said about the Audrey Horne-spin off: "David was talking about 'Mulholland Drive', he talked about like 'Audrey goes to Hollywood'. She's driving along Mulholland in this convertible car,"
In Mulholland Drive's car accident scene, his direction to Laura Harring was to act like a broken porcelain doll, which is the exact same direction he gave to Sherilyn Fenn for the Wild at Heart car accident scene. In fact Lynch said that this scene in Wild at Heart came from his impression of Fenn as a porcelain doll, and from the idea of seeing a porcelain doll breaking. He kept telling her about that, and that's how the scene was born.
It's kind of sad that Lynch hasn't worked with Fenn again. Would have been great to see her starring in Mulholland Drive.