Movies that should have had different release strategies?
In any way - number of theatres, marketing, PR etc.
I think Revolutionary Road would have benefited if it had released outside the Oscar season at a time when there was less adult fare. It should have had a wide release as well. A film that reunited DiCaprio and Winslet, even with challenging subject matter, definitely could have made more than $22 million at the domestic box office.
Another one I remember is 127 Hours. Fox Searchlight didn't do much to stem the conversation about the movie's graphic amputation scene (clearly believing it would add to the movie's must see stature) but the fact that it stopped at $18 million makes it clear they didn't do a good job of widening the movie's appeal and focusing on its life affirming qualities.
Live your own destiny imperfectly than live an imitation of someone else's perfectly