Nonsense abound...spoilers

1> How do you make the nanobots that can kill people based on their DNA? Put about 100 light sabers in a river of acid and stir it alot.

2> Where did the doctor go after leaving the prison? MI6 can't find her. She went home.

3> Criminal mastermind in a high-tech isolated prison cell under constant surveillance...still can orchestrate a dinner party for every single Spectre agent through a remote controlled eye.

4> Daughter drops toy and is allowed to walk away from villain to go get it. Doesnt find it in the middle of the floor. Then traverses secret base and hides under a coffee table in a room full of people until parents show up.

5> Villain has all the sheep herders in unnamed Italian village on speed dial in case he needs to force Bond down a certain street.

There are probably 50 others. But if you take these specific ones out of the movie...nothing material changes